Spironolactone
An aldosterone receptor antagonist that causes the kidneys to remove water and sodium from the body, with reduced losses of potassium.
Indications
- HTN
- Oedema of CCF
- Nephrotic syndrome
- Acsites
- PCOS – acne and female pattern hair loss.
Side effects.
- Skin rash
- Gynaecomastoa
- Hyperkaleamia
- GI upset
- Headache
Avoid w Lithium
Caution with
- ACE
- NSAIDS
- Diuretics
- Digoxin